Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
نویسندگان
چکیده
منابع مشابه
Pseudogene-derived small interference RNAs regulate gene expression in African Trypanosoma brucei.
Pseudogenes have been shown to acquire unique regulatory roles from more and more organisms. We report the observation of a cluster of siRNAs derived from pseudogenes of African Trypanosoma brucei using high through-put analysis. We show that these pseudogene-derived siRNAs suppress gene expression through RNA interference. The discovery that siRNAs may originate from pseudogenes and regulate g...
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ژورنال
عنوان ژورنال: Nature
سال: 2008
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature06904